Thyme



Scientific Name(s): Thymus vulgaris L.
Common Name(s): Common thyme, Garden thyme

Medically reviewed by Drugs.com. Last updated on July 8, 2020.

Jul 08, 2020 Animal data. Extracts of thyme and its individual chemical constituents have shown activity against various human pathogenic bacteria and fungi in in vitro studies, and thymol is commonly used in mouthwash preparations with chlorhexidine. Feb 19, 2021 All thyme, whether it is upright thyme or creeping thyme, tends to get a little wild looking if not shaped regularly. If you’re okay with your thyme getting a bit wild looking, you don’t need to cut your thyme to shape it. But, if you want a thyme plant that is a little more formal, you’ll want to shape your thyme plant yearly. Thyme is an extremely fragrant herb with thin, woody stems and small, pungent leaves. Available in both fresh or dried, this herb is easily found in most supermarkets year-round.

Thyme is an extremely fragrant herb with thin, woody stems and small, pungent leaves. Available in both fresh or dried, this herb is easily found in most supermarkets year-round. Thyme is a Mediterranean herb with dietary, medicinal, and ornamental uses. The flowers, leaves, and oil of thyme have been used to treat a range of symptoms and complaints.

Clinical Overview

Use

Thyme has primarily culinary uses. Thyme extracts and thymol have been used in cough mixtures and mouthwashes, as well as for skin conditions, especially fungal infections. Clinical trials are lacking to support these uses.

Dosing

Studies are lacking to guide clinical dosages.

Contraindications

Information is lacking.

Pregnancy/Lactation

Information regarding safety and efficacy in pregnancy and lactation is lacking.

Interactions

None well documented.

Adverse Reactions

Contact dermatitis and systemic allergy have been reported.

Toxicology

Information is lacking.

Scientific Family

  • Lamiaceae (Mint)

Botany

There are 6 recognized Thymus species, but many hybrids and varieties exist. T. vulgaris is a perennial plant native to some European and Asian countries. Thyme is a woody perennial (evergreen in mild winters) and is primarily grown as a herb. Numerous woody stems grow upward to form the 0.3 m height of the plant. The highly aromatic leaves are tiny, elliptical, and grey-green in color, and the margins roll under (revolute). Tiny tubular lilac flowers appear in late spring.PLANTS 2017, WHO 1999

History

Thyme was used as a symbol of elegance and grace in ancient Greece. Roman soldiers bathed in water infused with thyme for vigor, and Egyptians used thyme in the embalming process. Thyme sprigs were thought to be protective against plague, and thyme oil was used as an antiseptic during World War I. Teas made from thyme have been traditionally used for GI disorders and to treat intestinal parasites such as hookworm. Other traditional uses include treatment of bronchitis, as an agent in cough mixtures and mouthwashes, and as a topical application for acne and skin infections. Thyme has culinary applications and is commonly added to sausage meat and stuffing. It is used for its flavor in cosmetics and has been added to mouthwashes and toothpastes.Figueiredo 2008, Spiewak 2001

Chemistry

Although the essential oil of thyme has primarily been evaluated,Bozin 2006, Diaz-Maroto 2005, Kitajima 2004, Pina-Vaz 2004 some studies report on individual constituents isolated from the leaves and aerial plant parts.Chun 2001, Chun 2001, Dapkevicius 2002, Jukic 2007, Kitajima 2004, Takeuchi 2004 Composition varies with species, geographic distribution, and extraction methods.

Major chemical components include carvacrol and thymol, with cadalene, cineole, myrcene, terpinene, linalool, cymene, rosmarinic acid, and many other chemical constituents reported. Monoterpenoids, flavonoid glycosides, phenolic compounds, and polysaccharides have been identified by spectrophotometric analysis and thin-layer chromatography.Bozin 2006, Chun 2001, Chun 2001, Dapkevicius 2002, Diaz-Maroto 2005, Jukic 2007, Kitajima 2004, Kitajima 2004, Pina-Vaz 2004, Takeuchi 2004

Uses and Pharmacology

Carvacrol, thymol, linool, and thymol derivatives thymoquinone and thymohydroquinone inhibited acetylcholinesterase in laboratory experiments. Because of the decrease in hydrolysis of acetylcholine, a role in Alzheimer disease has been suggested; however, clinical trials are lacking to support this use.Figueiredo 2008, Jukic 2007

Antimicrobial effects

Animal data

Extracts of thyme and its individual chemical constituents have shown activity against various human pathogenic bacteria and fungi in in vitro studies, and thymol is commonly used in mouthwash preparations with chlorhexidine. Gram-positive bacteria (including Pseudomonas aeruginosa, Escherichia coli, and Salmonella and Shigella species) appear more susceptible than gram-negative bacteria.Bozin 2006, Figueiredo 2008, WHO 1999

Fungicidal activity on Candida species, Aspergillus, and other fungi has been demonstrated by carvacrol, thymol, and p-cymene, as well as the essential oil of thyme.Figueiredo 2008, Giordani 2004, Pina-Vaz 2004 Potentiation of amphotericin B against Candida albicans was demonstrated in one in vitro experiment.Giordani 2004

Clinical data

Clinical trials with thyme or thyme extract alone are lacking, with studies largely based on chemical elucidation and analysis and laboratory experimentation.

Thyme as thyme honey has been evaluated for efficacy in rhinosinusitisHashemian 2015 and radiation-induced xerostomia,Charalambous 2017 with suggested benefit from the phenolic constituents of thyme extract in the honey.

Thyme Herb

Antioxidant effects

Animal data

Extracts of thyme and individual chemical constituents have been evaluated for their antioxidant potential. Phenolic constituents demonstrated nitric oxide scavenging potential in one experimentVigo 2004 with other tests showing effects on lipid peroxidation, free radical scavenging, hydrogen ion donation, and activity in oil stability index tests.Bozin 2006, Dapkevicius 2002, Figueiredo 2008, Miura 2002

Clinical data

Clinical trials are lacking, with studies largely based on chemical elucidation and analysis and laboratory experimentation.

Antiplatelet activity

Antiplatelet aggregating activity has been demonstrated in vitro by thymol and a biphenyl compound extracted from thyme.Okazaki 2002

Bronchodilatory effect

A relaxant effect of thyme extract has been demonstrated on guinea pig tracheal chains. The bronchodilatory effect is suggested to be comparable with theophylline.Boskabady 2006

Detoxification

Increases in glutathione-S-transferase (GST) enzyme and liver mass were observed in mice fed thyme extracts (2%) daily for 7 days, leading the investigators to postulate a detoxifying role for thyme because the conjugation of glutathione to various toxins would be enhanced.Sasaki 2005

Dosing

Studies are lacking to guide clinical applications. Tinctures and the essential oil are used topically for fungal infections. Thyme infusions have been used as a gargle at 5% concentrations.WHO 1999

The pharmacokinetics of thymol in healthy adults have been evaluated. No free thymol was found in the blood or urine, with sulfate and glucuronide metabolites identified in the urine. A mean terminal elimination half-life was estimated to be 10 hours.Kohlert 2002

Pregnancy / Lactation

Information regarding safety and efficacy in pregnancy and lactation is lacking. Thyme tea is reported to be used traditionally postpartum to induce uterine contractions and expulsion of the placenta; however, clinical or pharmacological data are lacking, and despite widespread use of thyme, safety problems have not been reported.WHO 1999

Interactions

Information is lacking. Increases in GST levels were observed in experiments in mice.Sasaki 2005

Adverse Reactions

Information is lacking. Contact dermatitis and systemic reactions to thyme have been reported. Cross-reactivity with rosemary is a common finding with skin patch testing.Armisén 2003, Martínez-González 2007, Spiewak 2001

Toxicology

Information is lacking. Murine macrophage cell viability was unaffected at low to intermediate concentrations (less than 50 mcg/mL) of thyme extract.Vigo 2004 Mutagenic activity has not been found in a limited number of tests.WHO 1999

References

Armisén M, Rodríguez V, Vidal C. Photoaggravated allergic contact dermatitis due to Rosmarinus officinalis cross-reactive with Thymus vulgaris. Contact Dermatitis. 2003;48(1):52-53.12641580Boskabady MH, Aslani MR, Kiani S. Relaxant effect of Thymus vulgaris on guinea-pig tracheal chains and its possible mechanism(s). Phytother Res. 2006;20(1):28-33.16397917Bozin B, Mimica-Dukic N, Simin N, Anackov G. Characterization of the volatile composition of essential oils of some lamiaceae spices and the antimicrobial and antioxidant activities of the entire oils. J Agric Food Chem. 2006;54(5):1822-1828.16506839Charalambous A, Lambrinou E, Katodritis N, et al. The effectiveness of thyme honey for the management of treatment-induced xerostomia in head and neck cancer patients: A feasibility randomized control trial. Eur J Oncol Nurs. 2017;27:1-8. PMID: 28279391.28279391Chun H, Shin DH, Hong BS, Cho HY, Yang HC. Purification and biological activity of acidic polysaccharide from leaves of Thymus vulgaris L. Biol Pharm Bull. 2001;24(8):941-946.11510490Chun H, Jun WJ, Shin DH, Hong BS, Cho HY, Yang HC. Purification and characterization of anti-complementary polysaccharide from leaves of Thymus vulgaris L. Chem Pharm Bull. 2001;49(6):762-764.11411533Dapkevicius A, van Beek TA, Lelyveld GP, et al. Isolation and structure elucidation of radical scavengers from Thymus vulgaris leaves. J Nat Prod. 2002;65(6):892-896.12088434Diaz-Maroto MC, Diaz-Maroto Hidalgo IJ, Sanchez-Palomo E, Perez-Coello MS. Volatile components and key odorants of fennel (Foeniculum vulgare Mill.) and thyme (Thymus vulgaris L.) oil extracts obtained by simultaneous distillation-extraction and supercritical fluid extraction. J Agric Food Chem. 2005;53(13):5385-5389.15969523Figueiredo AC, Barroso JG, Pedro LG, Salgueiro L, Miguel MG, Faleiro ML. Portuguese Thymbra and Thymus species volatiles: chemical composition and biological activities. Curr Pharm Des. 2008;14(29):3120-3140.19075695Giordani R, Regli P, Kaloustian J, Mikaïl C, Abou L, Portugal H. Antifungal effect of various essential oils against Candida albicans. Potentiation of antifungal action of amphotericin B by essential oil from Thymus vulgaris. Phytother Res. 2004;18(12):990-995.15742351Hashemian F, Baghbanian N, Majd Z, et al. The effect of thyme honey nasal spray on chronic rhinosinusitis: a double-blind randomized controlled clinical trial. Eur Arch Otorhinolaryngol. 2015;272(6):1429-35. PMID: 25106547.25106547Herba Thymi. In: WHO Monographs on Selected Medicinal Plants. Vol 1. Geneva, Switzerland: World Health Organization; 1999: 259-266.Jukic M, Politeo O, Maksimovic M, Milos M, Milos M. In vitro acetylcholinesterase inhibitory properties of thymol, carvacrol and their derivatives thymoquinone and thymohydroquinone. Phytother Res. 2007;21(3):259-261.17186491Kitajima J, Ishikawa T, Urabe A. A new hydroxyjasmone glucoside and its related compounds from the leaf of thyme. Chem Pharm Bull (Tokyo). 2004;52(8):1013-1014.15305005Kitajima J, Ishikawa T, Urabe A, Satoh M. Monoterpenoids and their glycosides from the leaf of thyme. Phytochemistry. 2004;65(24):3279-3287.15561194Kohlert C, Schindler G, März RW, et al. Systemic availability and pharmacokinetics of thymol in humans. J Clin Pharmacol. 2002;42(7):731-737.12092740Martínez-González MC, Goday Buján JJ, Martínez Gómez W, Fonseca Capdevila E. Concomitant allergic contact dermatitis due to Rosmarinus officinalis (rosemary) and Thymus vulgaris (thyme). Contact Dermatitis. 2007;56(1):49-50.17177715Miura K, Kikuzaki H, Nakatani N. Antioxidant activity of chemical components from sage (Salvia officinalis L.) and thyme (Thymus vulgaris L.) measured by the oil stability index method. J Agric Food Chem. 2002;50(7):1845-1851.11902922Okazaki K, Kawazoe K, Takaishi Y. Human platelet aggregation inhibitors from thyme (Thymus vulgaris L.). Phytother Res. 2002;16(4):398-399.12112303Pina-Vaz C, Gonçalves Rodrigues A, Pinto E, et al. Antifungal activity of Thymus oils and their major compounds. J Eur Acad Dermatol Venereol. 2004;18(1):73-78.14678536Sasaki K, Wada K, Tanaka Y, Yoshimura T, Matuoka K, Anno T. Thyme (Thymus vulgaris L.) leaves and its constituents increase the activities of xenobiotic-metabolizing enzymes in mouse liver. J Med Food. 2005;8(2):184-189.16117610Spiewak R, Skorska C, Dutkiewicz J. Occupational airborne contact dermatitis caused by thyme dust. Contact Dermatitis. 2001;44(4):235-239.11260240Takeuchi H, Lu ZG, Fujita T. New monoterpene glucoside from the aerial parts of thyme (Thymus vulgaris L.). Biosci Biotechnol Biochem. 2004;68(5):1131-1134.15170120Thymus vulgaris L. USDA, NRCS. 2017. The PLANTS Database (http://plants.usda.gov, July 2017). National Plant Data Team, Greensboro, NC 27401-4901 USA. Accessed July 2017.Vigo E, Cepeda A, Gualillo O, Perez-Fernandez R. In-vitro anti-inflammatory effect of Eucalyptus globulus and Thymus vulgaris: nitric oxide inhibition in J774A.1 murine macrophages. J Pharm Pharmacol. 2004;56(2):257-263.15006885

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From Simple English Wikipedia, the free encyclopedia

Thyme

Thyme
Common thyme Thymus vulgaris
Scientific classification
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Thymus

Thyme (Thymus) (pronounced 'time') is a genus of perennial plants. There are about 350 different species of thyme. They are herbaceous plants and sub-shrubs. They can grow to about 40 cm tall. They are the family Lamiaceae and native to Europe, North Africa and Asia.

The stems are usually narrow, sometimes even wiry. The leaves are evergreen in most species. They are arranged in opposite pairs, oval, entire, and small, 4–20 mm long. The flowers are in dense terminal heads, with an uneven calyx, with the upper lip three-lobed, and the lower cleft; the corolla is tubular, 4–10 mm long, and white, pink or purple.

Thymus species are used as food plants by the larvae of some Lepidoptera species including Chionodes distinctella and Coleophora species.

History[change | change source]

Ancient Egyptians used thyme for embalming. The ancient Greeks used it in their baths and burnt it as incense in their temples. They believed that thyme was a source of courage. It was thought that the spread of thyme throughout Europe was thanks to the Romans, as they used it to purify their rooms. In the European Middle Ages, the herb was placed under pillows. This was done to help sleep and ward off nightmares. (Huxley 1992). In this period, women would also often give knights and warriors gifts that included thyme leaves. People believed it would bring courage to the bearer. Thyme was also used as incense and placed on coffins during funerals as it was supposed to assure passage into the next life.[1]

Cultivation[change | change source]

Thyme is widely grown as a herb. Usually it is grown for its strong flavour, which is due to its content of thymol.[2]

Thyme likes a hot sunny location with good-draining soil. It is planted in the spring and later grows as a perennial. It can be propagated by seed, cuttings, or by dividing rooted sections of the plant. It tolerates drought well.[3]

Thyme keeps its flavour on drying better than many other herbs.

Culinary use[change | change source]

Thyme is widely used for cooking. Thyme is a basic ingredient in French and Italian cuisines, and in those derived from them. It is also widely used in Caribbean cuisine.

Thyme is often used to flavour meats, soups and stews. It has a particular affinity to and is often used as a primary flavour with lamb, tomatoes and eggs.

Thyme, while flavourful, does not overpower and blends well with other herbs and spices. In French cuisine, along with bay and parsley it is a common component of the bouquet garni, and of herbes de Provence. In some Middle Eastern countries, the condiment za'atar contains thyme as a vital ingredient.

Thyme is sold both fresh and dried. The fresh form is more flavourful but also less convenient; storage life is rarely more than a week. While summer-seasonal, fresh thyme is often available year-round. Fresh thyme is commonly sold in bunches of sprigs. A sprig is a single stem snipped from the plant. It is composed of a woody stem with paired leaf or flower clusters ('leaves') spaced ½ to 1' apart. A recipe may measure thyme by the bunch (or fraction thereof), or by the sprig, or by the tablespoon or teaspoon. If the recipe does not specify fresh or dried, assume that it means fresh.

Thyme retains its flavour on drying better than many other herbs. Dried, and especially powdered thyme occupies less space than fresh, so less of it is required when substituted in a recipe. As with bay, thyme is slow to release its flavours so it is usually added early in the cooking process.

Medicinal use[change | change source]

Thyme

The essential oil of common thyme (Thymus vulgaris) is made up of 20-55% thymol.[4] Thymol, an antiseptic, is the main active ingredient in Listerine mouthwash.[5] Before the advent of modern antibiotics, it was used to medicate bandages.[6] It has also been shown to be effective against the fungus that commonly infects toenails.[7]

A tea made by infusing the herb in water can be used for cough and bronchitis.[4] Medicinally thyme is used for respiratory infections.[8] Because it is antiseptic, thyme boiled in water and cooled is very effective against inflammation of the throat.[8] The inflammation will normally disappear in 2 – 5 days. Other infections and wounds can be dripped with thyme.[8]

Thyme Oil

In traditional Jamaican childbirth practice, thyme tea is given to the mother after delivery of the baby. Its oxytocin-like effect causes uterine contractions and more rapid delivery of the placenta but this was said by Sheila Kitzinger to cause an increased prevalence of retained placenta.

Important species[change | change source]

Thymus vulgaris (common thyme or garden thyme) is a commonly used culinary herb. It also has medicinal uses. Common thyme is a Mediterranean perennial which is best suited to well-drained soils and enjoys full sun.

Thymus herba-barona (caraway thyme) is used both as a culinary herb and a groundcover, and has a strong caraway scent due to the chemical carvone.

Thymus × citriodorus (citrus thyme; hybrid T. pulegioides × T. vulgaris) is also a popular culinary herb, with cultivars selected with flavours of various Citrus fruit (lemon thyme, etc.)

Thymus pseudolanuginosus (woolly thyme) is not a culinary herb, but is grown as a ground cover.

Thymus serpyllum (wild thyme) is an important nectar source plant for honeybees. All thyme species are nectar sources, but wild thyme covers large areas of droughty, rocky soils in southern Europe (Greece is especially famous for wild thyme honey) and North Africa, as well as in similar landscapes in the Berkshire Mountains and Catskill Mountains of the northeastern US.

Cultivars[change | change source]

There are a number of different cultivars of thyme with established or growing popularity, including:

  • Lemon thyme—actually smells lemony
  • Variegated lemon thyme—with bi-color leaves
  • Orange thyme—an unusually low-growing, ground cover thyme that smells like orange
  • Creeping thyme—the lowest-growing of the widely used thymes, good for walkways
  • Silver thyme—white/cream variegated
  • English thyme—the most common
  • Summer thyme—unusually strong flavor

References[change | change source]

  1. 'englishplants.co.uk - Diese Website steht zum Verkauf! - Informationen zum Thema Plants'. www.englishplants.co.uk.no-break space character in |title= at position 20 (help)
  2. Huxley, A., ed. (1992). New RHS Dictionary of Gardening. Macmillan.
  3. http://www.global-garden.com.au/gardenherbs5.htm#Garden%20ThymeArchived 2007-10-12 at the Wayback Machine Herb File. Global Garden.
  4. 4.04.1Thymus Vulgaris. PDR for Herbal Medicine. Montvale, NJ: Medical Economics Company. p. 1184.
  5. Pierce, Andrea. 1999. American Pharmaceutical Association Practical Guide to Natural Medicines. New York: Stonesong Press. P. 338-340.
  6. Grieve, Maud (Mrs.). Thyme. A Modern Herbal. Hypertext version of the 1931 edition. Accessed: December 14, 2006. http://botanical.com/botanical/mgmh/t/thygar16.html
  7. Ramsewak RS, et al. In vitro antagonistic activity of monoterpenes and their mixtures against 'toe nail fungus' pathogens. Phytother Res. 2003 Apr;17(4):376-9.
  8. 8.08.18.2'Aromatherapy, Thyme, Essential oil'. Holisticonline.com. Retrieved 1 June 2013.CS1 maint: discouraged parameter (link)

Other sources[change | change source]

  • Huxley, A., ed. (1992). New RHS Dictionary of Gardening. Macmillan.
  • Rohde, E. S. (1920). A Garden of Herbs.

Thyme Bar

Thyme

Other websites[change | change source]

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